Polypropylene nanocomposites with two types of Bentonite as clay were prepared and evaluated as an alternative in food packaging applications. The manufacturing was carried out according to a proprietary method developed by Repsol. Mechanical, thermal and barrier properties were evaluated. Migration tests and analysis of residues were performed for safety assessment of nanocomposites to be used in articles intended to come into contact with food. The nature of migrants, using multiple analytical techniques, was determined to stablish if clay nanolayers migrate, in which case toxicological tests will have to be performed.